Exosomes
Exosomes are a powerful, next-generation way to rejuvenate your skin, refine texture, and support collagen production. By combining medical microneedling with exosome therapy, this medically-backed treatment enhances your skin’s natural repair process at a cellular level, leading to visibly smoother, clearer, and more radiant skin. At Harley Street Dermal, we focus on using exosome therapy to enhance your skin using your body’s own biological repair mechanisms, not artificial shortcuts.
What Is Exosome Microneedling and How Does It Work?
Exosome microneedling is a minimally invasive, regenerative skin treatment that combines medical-grade microneedling with DP Exo-Skin™, an advanced exosome glide developed by Dermapen.
EXO-SKIN™ is derived from ethically sourced human umbilical cord mesenchymal stem cells (MSCs), considered one of the youngest and most biologically active sources of exosomes. These exosomes are cell-free and non-living, acting instead as powerful signalling molecules that help guide skin regeneration, cellular repair, and collagen production leading to smoother skin texture, improved firmness, more even skin tone, and stronger overall skin quality over time.
The formulation utilises patented HLA-G COMPLEXA™ technology, which is designed to be immune-tolerant and to support skin repair while minimising inflammation. This makes it particularly suitable for regenerative skin treatments where healing quality and skin resilience are key.
During treatment, DP Exo-Skin™ is first applied to the skin, and microneedling is then performed over it. The ultra-fine needles create controlled microscopic channels, allowing the exosomes to be delivered into the skin where they can actively support and guide the body’s natural repair processes.
For optimal results, we typically recommend a course of 3–6 treatments, spaced approximately 4 weeks apart, depending on your skin concerns and goals. To maintain and build on your results, a top-up session every 3–6 months is advised. This helps keep the skin in an active state of regeneration, prolonging the improvements achieved during your initial treatment course.
Why Consider Having Exosomes Treatment?
- Exosome microneedling is ideal for anyone looking to improve skin texture, reduce fine lines, acne scarring, enlarged pores, and achieve a healthier, more radiant complexion.
- It is particularly effective for targeting pigmentation, sun damage, early signs of ageing, and dull or compromised skin by enhancing cellular repair and regeneration.
- Exosome microneedling can be safely used on delicate areas, such as under the eyes or around the mouth, due to its regenerative and inflammation-reducing properties.
- By incorporating exosomes with microneedling, results are enhanced beyond microneedling alone, with improved healing, stronger collagen stimulation, and more consistent long-term skin quality improvements.
Why choose Harley Street Dermal for Exosomes Microneedling?
- Expert-Led Care– All treatments are carried out or overseen by a qualified GP, Dr Aliaa Ahmed, who has advanced training in aesthetic medicine and dermatology. With years of clinical experience, she brings a deep understanding of both skin function and cosmetic outcomes allowing for safe targeting of complex skin concerns like acne scars, pigmentation, rosacea, or skin laxity.
- We personalise your treatment– this includes a combination of different treatments, including peels, injectables and medical-grade skincare, to deliver results that work specifically for your skin, not a one-size-fits-all
- We use DP Exo-Skin™, an advanced exosome glide developed by Dermapen which is clinically proven to improve skin regeneration, cellular repair, and collagen production
- Our treatments are evidence-based– our microneedling and exosome/PRP/PRF combination protocols are all based on actual studies and science, not guesswork
- We have a proven track-record– just have a look at our hundreds of before/after images that showcase only a small selection of our brilliant work over the years
- Our reviews speak for themselves- with over 1000 5-star Reviews on Google and Trustpilot, it’s not difficult to imagine that patient satisfaction is our top priority
- Our prices are competitive and reasonable. We are more affordable than most other clinics for the uncompromising high quality results that we deliver at such a prestigious location
- We are based at a beautiful & clean first-class clinic at the world-renowned Harley Street, located at the heart of London
- We care that you care– our doctors are easily and directly contactable by anyone after treatment to ensure that you are recovering safely and with the results you want. This includes reviewing treatment where necessary and without charge.
At A Glance
Procedure time: 30 mins
Frequency: 3-6 sessions 4 weeks apart then maintenance every 3-6 months
Recovery: Mild redness for a few days
Targets: Pigmentation, acne scarring, ageing, rosacea
Pricing: From £450, see fees page.
Pain: Usually minimal, topical anaesthetic used
Only natural-looking results
10 years experience and over 1,000 5-star reviews on Google and Trustpilot
Frequently Asked Questions
How do I know if exosomes microneedling is right for me?
Exosomes Microneedling is suitable for most skin types and concerns, especially if you’re struggling with acne scarring, pigmentation, enlarged pores, early signs of ageing, or overall dullness. If you prefer a regenerative, minimally-invasive approach with minimal downtime and proven results, then exosomes microneedling is an excellent choice to consider. Our doctors will always conduct a full consultation to ensure that you are suitable for treatment and can explore potential alternative solutions if you aren’t.
Will the results look natural?
Yes. Exosomes Microneedling enhances your skin’s own regenerative ability, meaning the improvements develop gradually and naturally over time. You won’t look “done” or artificially altered, just refreshed, smoother, and more luminous. Because it works with your body’s biology, the result is healthier, stronger skin, not an over-corrected appearance.
Is the treatment painful?
Most patients find Exosomes microneedling very tolerable. A topical numbing cream is applied before the procedure to ensure comfort. You may feel a light scratching or vibration but discomfort is usually minimal and brief.
What should I expect on the day?
Your doctor would usually welcome you and start with a detailed consultation. This would include discussing any previous treatments you’ve had, what your understanding of the treatment is and exploring your goals and expectations. They will also discuss the nature of the exosomes microneedling procedure and related risks. If you are agreeable, the doctor will then usually conduct the treatment by first taking a pre-treatment photo and then applying topical anaesthetic while you complete the necessary medical and consent forms. After the treatment is complete, the doctor will then explain any relevant aftercare and offer you information on how to contact them for questions or any follow-up you might require. Our doctors are always contactable directly for any clinical queries by email. You may also be offered supplementary treatments, such as medical-grade skincare creams which could further enhance the effects of the treatment.
What should I expect afterwards?
Redness and sensitivity are common for 24–48 hours. Some clients may experience light flaking, dryness, or tightness in the days that follow as the skin regenerates. By day 3–5, most people see noticeable glow and smoother skin texture. You can resume normal skincare within a few days, and full collagen stimulation continues for up to 6 weeks post-treatment.
Are there any precautions I should take beforehand or afterwards?
Before treatment, avoid active skincare ingredients (like retinoids or acids), tanning, and waxing for 5–7 days. Afterwards, avoid hot environments (steam rooms, saunas, strenuous workouts), exfoliation, and direct sun exposure for 48–72 hours. SPF must be worn daily to protect your new skin. A gentle, hydrating routine will be advised to maximise your results and prevent irritation.
Is there any follow-up after the procedure?
Exosomes Microneedling often requires successive treatments for the best results. If you’re undergoing a course of treatments, we’ll monitor your progress at each visit and adjust your plan as needed. You’re welcome to check in with us virtually or in clinic to discuss your skin’s response or if there are any concerns.
Your New Look Starts Here
Book Your Consultation Now
WhatsApp us on 020 3983 2058 to check our availability